下肢外周动脉疾病的磁共振成像：最新进展
MRI in Lower Extremity Peripheral Arterial Disease: Recent Advancements.
作者信息
Pollak Amy W, Kramer Christopher M
机构信息
Department of Medicine, Cardiovascular Imaging Center, University of Virginia Health System, University of Virginia, Charlottesville, VA.
出版信息
Curr Cardiovasc Imaging Rep. 2013 Feb 1;6(1):55-60. doi: 10.1007/s12410-012-9175-z.
Abstract
Evaluation of peripheral arterial disease by cardiovascular magnetic resonance imaging continues to develop. Of the clinical diagnostics tests currently available, magnetic resonance angiography is well established as one of the preferred techniques for determining areas of arterial occlusive disease affecting the lower extremities. Despite this, there have been new developments in non-gadolinium based contrast-enhanced studies as well as testing done at higher field strength scanners. In the research arena, magnetic resonance spectroscopy, calf muscle perfusion imaging and atherosclerotic plaque evaluation all have made significant advancements over the last year. These techniques are gaining traction as surrogate endpoints in clinical trials of novel therapeutics aimed at alleviating symptoms in patients with peripheral arterial disease.
摘要
心血管磁共振成像对外周动脉疾病的评估仍在不断发展。在目前可用的临床诊断测试中，磁共振血管造影已成为确定影响下肢动脉闭塞性疾病区域的首选技术之一。尽管如此，基于非钆对比增强研究以及在更高场强扫描仪上进行的测试也有了新进展。在研究领域，磁共振波谱、小腿肌肉灌注成像和动脉粥样硬化斑块评估在过去一年都取得了重大进展。在旨在缓解外周动脉疾病患者症状的新型治疗药物的临床试验中，这些技术作为替代终点正越来越受到关注。
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