Semple H C, Ball S F
Lions Eye Research Laboratories, LSU Eye Center, New Orleans 70112.
Am J Ophthalmol. 1990 May 15;109(5):518-22. doi: 10.1016/s0002-9394(14)70680-4.
The pigment dispersion syndrome is associated with a secondary open-angle glaucoma most commonly found in young, myopic, white males. We studied 20 cases (38 eyes) of pigment dispersion syndrome in black individuals as defined by heavy deposition on the corneal endothelium and trabecular meshwork with increased intraocular pressure but no other ocular abnormalities. The 20 patients were a homogeneous group that was typified by older age distribution (average, 73 years), a preponderance of hyperopia (median refraction, +2.15 diopters spherical equivalent), female gender (19 women, one man), no iris transillumination defects (zero of 38 eyes), and flatter iris insertion into the ciliary body. We believe that this homogeneous group of black individuals with pigment dispersion and atypical features represents a pigment dispersion syndrome associated with older age, hyperopia, and female sex preponderance, in the black race.
色素播散综合征与继发性开角型青光眼相关，最常见于年轻、近视的白人男性。我们研究了20例（38只眼）黑人色素播散综合征患者，其定义为角膜内皮和小梁网有大量沉着物，眼压升高，但无其他眼部异常。这20例患者是一个同质群体，其特点是年龄分布较大（平均73岁），远视占优势（平均球镜当量为+2.15屈光度），女性居多（19名女性，1名男性），无虹膜透照缺损（38只眼中为零），虹膜插入睫状体较扁平。我们认为，这一具有色素播散和非典型特征的黑人同质群体代表了黑人种族中与老年、远视和女性优势相关的色素播散综合征。
