Department of Obstetrics, Aberdeen Maternity Hospital, Aberdeen, UK.
BJOG. 2013 Apr;120(5):621-7. doi: 10.1111/1471-0528.12120. Epub 2013 Jan 23.
To assess the outcomes of pregnancy following postpartum haemorrhage (PPH) in the first pregnancy.
Cohort study.
Aberdeen Maternity Hospital, Scotland, UK.
All women with first deliveries recorded in the Aberdeen Maternity and Neonatal Databank (AMND) between 1986 and 2005.
All women identified from the AMND were classified into exposed and unexposed cohorts, according to whether or not they had PPH in their first delivery. They were then linked to any records of a second pregnancy.
Any second pregnancy, time to second pregnancy, early or late pregnancy loss, and prevalence of PPH in the second pregnancy.
Out of 34 334 women, 10% had a PPH in their first pregnancy. There was no statistically significant difference in the time to a second pregnancy, nor in the outcome of that second pregnancy, between women who had experienced a PPH in their first pregnancy and women who had not. For women with a caesarean delivery, there was a significant reduction in the proportion conceiving again, comparing the exposed and unexposed cohorts.
From this cohort study we can conclude that if a PPH occurs in a first pregnancy, there is no delay in achieving a second pregnancy, and no detrimental effect on the outcome of that pregnancy. Significantly fewer women conceive a second pregnancy if they have a caesarean section in their first pregnancy that is complicated by PPH.
评估首次产后出血(PPH)后妊娠的结局。
队列研究。
英国苏格兰阿伯丁妇产医院。
在 1986 年至 2005 年期间,阿伯丁母婴数据库(AMND)中记录的所有首次分娩的妇女。
根据她们在首次分娩中是否有 PPH,将 AMND 中确定的所有妇女分为暴露组和未暴露组。然后将她们与任何第二胎妊娠的记录进行关联。
任何第二胎妊娠、第二胎妊娠的时间、早期或晚期妊娠丢失以及第二胎妊娠中 PPH 的发生率。
在 34334 名妇女中,10%的妇女在首次妊娠中发生 PPH。在经历过首次妊娠 PPH 的妇女和未经历过 PPH 的妇女之间,第二次妊娠的时间以及第二次妊娠的结局没有统计学上的显著差异。对于剖宫产的妇女,与未暴露组相比,再次怀孕的比例显著降低。
从这项队列研究中我们可以得出结论,如果首次妊娠中发生 PPH,不会延迟第二次妊娠的时间,也不会对该妊娠的结局产生不利影响。如果首次妊娠中 PPH 并发剖宫产,再次怀孕的妇女明显减少。