Bates C J, Burr M K, St Leger A S
Age Ageing. 1979 Aug;8(3):177-82. doi: 10.1093/ageing/8.3.177.
Plasma vitamin C, total and high density lipoprotein (HDL) cholesterol and cortisol levels were measured in a random sample of 337 elderly subjects living at home in S. Wales; measurements of relative body weight and information about fruit intake, smoking habits and symptoms of cardiovascular disease were also collected. There was a sex difference, over all age groups, in plasma vitamin C and in total HDL cholesterol levels. Plasma vitamin C was strongly correlated with fruit intake in both sexes. Both HDL cholesterol and low and very density lipoprotein (LDL + VLDL) cholesterol levels tended to increase with increasing plasma vitamin C but this reached significance only for the LDL + VLDL fraction. In addition, HDL cholesterol was negatively correlated with Quetelet's index in the women. Symptoms and medication for heart disease did not correlate significantly with plasma vitamin C or with HDL cholesterol levels, but reported angina showed a weak positive association with total cholesterol in the men, and there was some evidence of increased cortisol levels in subjects with heart disease.
对居住在南威尔士家中的337名老年受试者的随机样本测量了血浆维生素C、总高密度脂蛋白（HDL）胆固醇和皮质醇水平；还收集了相对体重测量值以及水果摄入量、吸烟习惯和心血管疾病症状等信息。在所有年龄组中，血浆维生素C和总HDL胆固醇水平存在性别差异。血浆维生素C与男女双方的水果摄入量都密切相关。HDL胆固醇以及低密度和极低密度脂蛋白（LDL + VLDL）胆固醇水平都倾向于随着血浆维生素C的增加而升高，但这仅在LDL + VLDL部分达到显著水平。此外，女性的HDL胆固醇与奎特利指数呈负相关。心脏病的症状和用药与血浆维生素C或HDL胆固醇水平无显著相关性，但报告的心绞痛与男性的总胆固醇呈弱正相关，并且有证据表明心脏病患者的皮质醇水平有所升高。
