Hooper P L, Hooper E M, Hunt W C, Garry P J, Goodwin J S
Int J Vitam Nutr Res. 1983;53(4):412-9.
Vitamin status may be related to serum lipid-lipoprotein levels. We tested this hypothesis in a group of 270 healthy elderly men and women over 60 years of age. Vitamin status was determined from dietary intakes and biochemical analysis of plasma. Fasting lipid profile included triglycerides, total cholesterol, low-density lipoprotein-cholesterol (LDL-C), and high-density lipoprotein-cholesterol (HDL-C). Correlations have been adjusted by partial correlation for age, physical activity, body mass index, and alcohol consumption. Neither vitamin E intake nor ascorbic acid intake nor ascorbic acid plasma levels correlated with any lipids measured. HDL-C levels did not correlate with any vitamin parameters. In men, vitamin A blood levels correlated with LDL-C, triglyceride, and total cholesterol levels. In women, total cholesterol levels correlated inversely with thiamine and riboflavin blood status and with dietary intake of vitamins B6, D, and niacin. LDL-C plasma values were also inversely correlated with both intake and plasma vitamin D levels and intakes of riboflavin and vitamin B12 in women.
维生素状态可能与血清脂质-脂蛋白水平有关。我们在一组270名60岁以上的健康老年男性和女性中验证了这一假设。维生素状态通过饮食摄入量和血浆生化分析来确定。空腹血脂谱包括甘油三酯、总胆固醇、低密度脂蛋白胆固醇（LDL-C）和高密度脂蛋白胆固醇（HDL-C）。已通过偏相关对年龄、身体活动、体重指数和饮酒量进行了相关性校正。维生素E摄入量、抗坏血酸摄入量以及抗坏血酸血浆水平均与所测的任何脂质均无相关性。HDL-C水平与任何维生素参数均无相关性。在男性中，维生素A血水平与LDL-C、甘油三酯和总胆固醇水平相关。在女性中，总胆固醇水平与硫胺素和核黄素的血液状态以及维生素B6、D和烟酸的饮食摄入量呈负相关。女性的LDL-C血浆值也与维生素D的摄入量和血浆水平以及核黄素和维生素B12的摄入量呈负相关。
