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The case for more intensive use of statins.

作者信息

Fulcher Jordan, Keech Anthony

机构信息

NHMRC Clinical Trials Centre - School of Medicine, University of Sydney, Camperdown, NSW, Australia.

出版信息

Ther Adv Chronic Dis. 2012 Sep;3(5):201-10. doi: 10.1177/2040622312454045.

DOI:10.1177/2040622312454045
PMID:23342235
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3539269/
Abstract
摘要

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本文引用的文献

1
The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials.他汀类药物降低 LDL 胆固醇对低血管疾病风险人群的影响：27 项随机试验个体数据的荟萃分析。
Lancet. 2012 Aug 11;380(9841):581-90. doi: 10.1016/S0140-6736(12)60367-5. Epub 2012 May 17.
2
Effects on 11-year mortality and morbidity of lowering LDL cholesterol with simvastatin for about 5 years in 20,536 high-risk individuals: a randomised controlled trial.辛伐他汀降低 LDL 胆固醇 5 年对 20536 名高危个体 11 年死亡率和发病率的影响：一项随机对照试验。
Lancet. 2011 Dec 10;378(9808):2013-2020. doi: 10.1016/S0140-6736(11)61125-2. Epub 2011 Nov 22.
3
Statins and intracerebral hemorrhage: a retrospective cohort study.他汀类药物与脑出血：一项回顾性队列研究。
Arch Neurol. 2012 Jan;69(1):39-45. doi: 10.1001/archneurol.2011.228. Epub 2011 Sep 12.
4
Risk of incident diabetes with intensive-dose compared with moderate-dose statin therapy: a meta-analysis.与中等剂量他汀类药物治疗相比，强化剂量他汀类药物治疗的新发糖尿病风险：一项荟萃分析。
JAMA. 2011 Jun 22;305(24):2556-64. doi: 10.1001/jama.2011.860.
5
Predictors of new-onset diabetes in patients treated with atorvastatin: results from 3 large randomized clinical trials.阿托伐他汀治疗患者新发糖尿病的预测因素：3 项大型随机临床试验的结果。
J Am Coll Cardiol. 2011 Apr 5;57(14):1535-45. doi: 10.1016/j.jacc.2010.10.047.
6
Statin myopathy: significant problem with minimal awareness by clinicians and no emphasis by clinical investigators.他汀类药物相关性肌病：临床医生认识不足且临床研究人员未予重视的重要问题。
Angiology. 2011 Jul;62(5):415-21. doi: 10.1177/0003319710395560. Epub 2011 Mar 18.
7
Intensive lowering of LDL cholesterol with 80 mg versus 20 mg simvastatin daily in 12,064 survivors of myocardial infarction: a double-blind randomised trial.辛伐他汀日剂量 80 毫克与 20 毫克对心肌梗死后 12064 例存活者的 LDL 胆固醇的强化降低作用：一项双盲随机试验。
Lancet. 2010 Nov 13;376(9753):1658-69. doi: 10.1016/S0140-6736(10)60310-8. Epub 2010 Nov 8.
8
Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials.更强化降低 LDL 胆固醇的疗效和安全性：来自 26 项随机试验中 170000 名参与者数据的荟萃分析。
Lancet. 2010 Nov 13;376(9753):1670-81. doi: 10.1016/S0140-6736(10)61350-5. Epub 2010 Nov 8.
9
Dose comparisons of clopidogrel and aspirin in acute coronary syndromes.氯吡格雷和阿司匹林在急性冠脉综合征中的剂量比较。
N Engl J Med. 2010 Sep 2;363(10):930-42. doi: 10.1056/NEJMoa0909475.
10
ACCORD glycemia results continue to puzzle.ACCORD血糖研究结果仍令人困惑。
Diabetes Care. 2010 May;33(5):1149-50. doi: 10.2337/dc10-0432.