Institut national de santé publique du Québec, Montréal, Canada.
J Low Genit Tract Dis. 2013 Apr;17(2):147-53. doi: 10.1097/LGT.0b013e31825c3915.
We assessed temporal trend in the incidence and prevalence of genital warts (GWs) in the province of Quebec, Canada, between 1998 and 2007 as a baseline for future assessment of the impact of Quebec human papillomavirus vaccination program.
Data on GWs were obtained from the linkage of the physician service claims and the public insurance drug plan databases. Genital warts were identified through a prescription of podofilox, a medical procedure code specific to GWs or a diagnosis code for viral warts followed by a prescription of imiquimod or fluorouracil within 2 weeks. An episode was considered incident if it was preceded by a 12-month interval period free of GWs care.
During the study period, a total of 27,138 episodes of GWs occurred among 24,267 individuals. The age-standardized incidence rate increased over time in men and women. The highest incidence was observed in women aged 20 to 24 years (391.9/100,000) and in men aged 25 to 29 years (383.3/100,000). Similar trends in prevalence were observed.
The incidence and prevalence of GWs has increased among the population covered by the public insurance drug plan in Quebec.
评估加拿大魁北克省 1998 年至 2007 年间生殖器疣（GWs）的发病率和流行率的时间趋势，作为未来评估魁北克人乳头瘤病毒疫苗接种计划影响的基线。
GWs 的数据来自医生服务索赔和公共保险药物计划数据库的链接。生殖器疣通过podofilox 的处方、特定于 GWs 的医疗程序代码或病毒疣的诊断代码以及在 2 周内处方咪喹莫特或氟尿嘧啶来识别。如果一个 GWs 治疗间隔期为 12 个月，则认为该病例为新发病例。
在研究期间，24267 名个体中有 27138 例 GWs 发作。男性和女性的年龄标准化发病率随时间增加。在 20 至 24 岁的女性（391.9/100,000）和 25 至 29 岁的男性（383.3/100,000）中观察到最高的发病率。流行率也观察到类似的趋势。
在魁北克公共保险药物计划覆盖的人群中，GWs 的发病率和流行率有所增加。
