Charles University in Prague, Second Faculty of Medicine, V Úvalu 84, 150 06 Prague 5, Czech Republic.
Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Int J Infect Dis. 2015 Jun;35:29-33. doi: 10.1016/j.ijid.2015.04.002. Epub 2015 Apr 11.
To describe the burden and the predictors of genital warts (GWs) in Czech men and women.
A population-based cross-sectional study was conducted of 32 974 randomly selected health clinic attendees from all 14 regions of the Czech Republic. Information on GWs and lifestyle behaviour was collected using a questionnaire.
Results revealed a 5.8% prevalence rate of self-reported GWs in the Czech population aged 16-55 years. There was an increase in the incidence of GWs in the years 2010-2013 when compared to lifetime incidence rates, from 205.4 (95% confidence interval (CI) 191.0-219.7) to 441.8 (95% CI 393.1-490.6) per 100 000 person-years. No significant differences were observed between genders. The strongest risk factors found for GWs were an infected sexual partner (adjusted odds ratio (OR) 114.3, 95% CI 78.9-165.4) and a high number of lifetime sexual partners (adjusted OR 3.36, 95% CI 2.72-4.17 for >14 partners vs. one partner). A novel finding was that 22.7% (95% CI 20.9-24.6%) of participants claimed that the pathology had disappeared spontaneously without medical assistance.
The results provide baseline information for the development and monitoring of prevention strategies against GWs in the Czech Republic.
描述捷克男女人群中生殖器疣（GWs）的负担和预测因素。
在捷克共和国所有 14 个地区的 32974 名随机选择的健康诊所就诊者中开展了一项基于人群的横断面研究。使用问卷收集了 GWs 和生活方式行为的信息。
结果显示，捷克年龄在 16-55 岁的人群中，自我报告的 GWs 患病率为 5.8%。与终身发病率相比，2010-2013 年 GWs 的发病率增加，从每 10 万人年 205.4（95%置信区间（CI）191.0-219.7）增至 441.8（95% CI 393.1-490.6）。男女之间没有观察到显著差异。发现 GWs 的最强风险因素是感染性性伴侣（调整后的优势比（OR）114.3，95%CI 78.9-165.4）和高数量的终身性伴侣（调整后的 OR 3.36，95%CI 2.72-4.17，与 >14 个性伴侣相比，与一个性伴侣相比）。一个新发现是，22.7%（95%CI 20.9-24.6%）的参与者声称该病理学未经医疗帮助而自发消失。
这些结果为捷克共和国制定和监测针对 GWs 的预防策略提供了基线信息。
