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1
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Nat Rev Cancer. 2012 Nov;12(11):736-7. doi: 10.1038/nrc3386. Epub 2012 Oct 18.
2
TAp63 is a master transcriptional regulator of lipid and glucose metabolism.
Cell Metab. 2012 Oct 3;16(4):511-25. doi: 10.1016/j.cmet.2012.09.006.
3
TAp73 depletion accelerates aging through metabolic dysregulation.
Genes Dev. 2012 Sep 15;26(18):2009-14. doi: 10.1101/gad.197640.112.
4
The p53 family grows old.
Genes Dev. 2012 Sep 15;26(18):1997-2000. doi: 10.1101/gad.202648.112.
5
Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence.
Cell. 2012 Jun 8;149(6):1269-83. doi: 10.1016/j.cell.2012.04.026.
6
ΔNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation.
Development. 2012 Feb;139(4):772-82. doi: 10.1242/dev.071191.
7
A novel heterozygous point mutation in the p63 gene in a patient with ectodermal dysplasia associated with B-cell leukemia.
Pediatr Dermatol. 2011 Nov-Dec;28(6):707-710. doi: 10.1111/j.1525-1470.2011.01474.x. Epub 2011 Sep 9.
8
Distinct p53 transcriptional programs dictate acute DNA-damage responses and tumor suppression.
Cell. 2011 May 13;145(4):571-83. doi: 10.1016/j.cell.2011.03.035.
9
Structures of p63 DNA binding domain in complexes with half-site and with spacer-containing full response elements.
Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6456-61. doi: 10.1073/pnas.1013657108. Epub 2011 Apr 4.
10
p73 deficiency results in impaired self renewal and premature neuronal differentiation of mouse neural progenitors independently of p53.
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