Batra Sandeep, Wadhwa Jyoti, Vaid Ashok K, Sharma Neelam
Department of Medical Oncology, Medanta, The Medicity, Gurgaon, Haryana, India.
BMJ Case Rep. 2013 Jan 22;2013:bcr2012008066. doi: 10.1136/bcr-2012-008066.
This is a case of acute splenic and bilateral renal infarction in a patient with non-small cell lung carcinoma during chemotherapy with gemcitabine and cisplatin. Till date, bilateral renal infarction following gemcitabine and cisplatin has been reported only once in the past. The case that is being reported has had acute splenic and bilateral renal infarct and has not been reported previously. Splenic and renal infarction should be considered in the differential diagnosis of excruciating abdominal pain and backache in a patient on gemcitabine-based and cisplatin-based chemotherapy.
这是一例非小细胞肺癌患者在接受吉西他滨和顺铂化疗期间发生急性脾梗死和双侧肾梗死的病例。迄今为止,既往仅报道过1例吉西他滨和顺铂治疗后发生双侧肾梗死的病例。本报告的该病例发生了急性脾梗死和双侧肾梗死,此前未见报道。在以吉西他滨和顺铂为基础进行化疗的患者出现剧烈腹痛和背痛时,鉴别诊断应考虑脾梗死和肾梗死。