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冠状动脉搭桥手术中的人口统计学变化及其对死亡率和发病率的影响。

Demographic changes in coronary artery bypass surgery and its effect on mortality and morbidity.

作者信息

Acinapura A J, Jacobowitz I J, Kramer M D, Adkins M S, Zisbrod Z, Cunningham J N

机构信息

Department of Cardiovascular and Thoracic Surgery, St. Vincent's Hospital, Brooklyn, NY.

出版信息

Eur J Cardiothorac Surg. 1990;4(4):175-81. doi: 10.1016/1010-7940(90)90001-g.

Abstract

Over the past 4-5 years, possibly with the advent of percutaneous transluminal coronary angioplasty (PTCA), there has been a changing patient population for coronary artery bypass surgery (CABS) with a gradual increase in the operative mortality. In an attempt to analyze the changing demographics in patients undergoing CABS and its effect on operative mortality, we analyzed data from 5536 consecutive patients undergoing isolated CABS. There was 4151 patients less than 70 years of age and 1385 patients greater than 70 years. Reoperative CABS procedures were performed in 385 patients, and CABS for post infarction unstable angina pectoris was performed in 578 patients. During the same time period, 2910 patients underwent PTCA. The mean age of bypass patients was 68.5 years with 38% being 70 years or older. The left ventricular ejection fraction in patients undergoing CABS averaged 38%. The average number of bypasses performed was 3.1. In comparison, patients presenting for PTCA were younger (average age 55), had normal ejection fractions (average 55%) and were predominantly treated for single or double vessel disease. The hospital mortality for elective CABS in patients less than 70 years of age was 1.8%, for reoperative CABS 3.6%, for post infarction unstable angina pectoris 4%, and for patients greater than 70 years 8%, for a combined operative mortality of 4.8%. These data suggest that because of the increasing number of elderly patients (greater than 70 years of age), and the increasing number of reoperative CABS cases and acute myocardial infarction patients with unstable angina pectoris presenting for CABS, the operative mortality will continue to rise.

摘要

在过去4至5年中,可能随着经皮腔内冠状动脉成形术(PTCA)的出现,接受冠状动脉搭桥手术(CABS)的患者群体发生了变化,手术死亡率逐渐上升。为了分析接受CABS患者的人口统计学变化及其对手术死亡率的影响,我们分析了5536例连续接受单纯CABS患者的数据。其中年龄小于70岁的患者有4151例,年龄大于70岁的患者有1385例。385例患者接受了再次CABS手术,578例患者因心肌梗死后不稳定型心绞痛接受了CABS手术。在同一时期,2910例患者接受了PTCA。搭桥患者的平均年龄为68.5岁,其中38%为70岁及以上。接受CABS患者的左心室射血分数平均为38%。平均搭桥数量为3.1。相比之下,接受PTCA的患者更年轻(平均年龄55岁),射血分数正常(平均55%),主要治疗单支或双支血管病变。70岁以下择期CABS患者的医院死亡率为1.8%,再次CABS患者为3.6%,心肌梗死后不稳定型心绞痛患者为4%,70岁以上患者为8%,综合手术死亡率为4.8%。这些数据表明,由于老年患者(大于70岁)数量增加,以及再次CABS病例数量增加,还有因不稳定型心绞痛前来接受CABS的急性心肌梗死患者数量增加,手术死亡率将继续上升。

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