Department of Pathology, Yeungnam University College of Medicine, 170 Hyeonchung-ro, Nam-gu, Daegu, Rep of Korea.
Diagn Pathol. 2013 Jan 24;8:12. doi: 10.1186/1746-1596-8-12.
Vascular abnormality of the intestine is rare, except angiodysplasia. We report on an unusual case of atypical florid vascular proliferations of the appendix. A 41-year old male presented with melena. Adhesioned blood clots in the appendiceal orifice were observed by colonoscopy. He underwent laparoscopic appendectomy. Microscopically, a tiny exophytic polypoid mass was observed. The mass showed pyogenic granuloma-like features in the superficial portion and infiltrative florid vascular proliferations in the deeper portion. Endothelial cells showed minimal nuclear atypia, and mitotic figures were observed infrequently and showed positivity for CD31 and CD34 and negativity for HHV-8. Differential diagnoses include from benign vascular tumor to angiosarcoma or Kaposi's sarcoma, but this lesion does not fit the description of any defined vascular entity. We diagnosed atypical florid vascular proliferations and the patient has been well during the five-month postoperative follow-up.
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肠道血管异常罕见，除了动静脉畸形。我们报告一个阑尾不典型弥漫性血管增生的罕见病例。一名 41 岁男性因黑便就诊。结肠镜检查观察到阑尾口有粘连的血凝块。他接受了腹腔镜阑尾切除术。镜下观察到一个微小的外生性息肉样肿块。肿块的浅层呈化脓性肉芽肿样特征，深层呈弥漫性血管增生。内皮细胞核异型性最小，有丝分裂象少见，CD31 和 CD34 阳性，HHV-8 阴性。鉴别诊断包括从良性血管肿瘤到血管肉瘤或卡波西肉瘤，但该病变不符合任何已定义的血管实体的描述。我们诊断为不典型弥漫性血管增生，患者在术后 5 个月的随访中情况良好。
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