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[升压药和降压药联合作用下动脉血压变化的特征]

[Character of arterial pressure changes under combined action of pressor and depressor agents].

作者信息

Lioznov M V, Tkachenko B I

出版信息

Biull Eksp Biol Med. 1990 Jan;109(1):13-5.

PMID:2334787
Abstract

It is shown in acute experiments in cats that byphasic arterial pressure changes occurred due to action of two heterodirectional and equivalent humoral stimuli. Magnitudes of both initial depressor and following pressor phases were authentically less than the ones due to separate action of those stimuli. It is noticed that the character of sum reaction depends neither on action mechanisms of vasoactive agents in the blood circulation system nor differences in the latent period of the effect of those drugs, but connected with intensiveness of stimuli. Predominance of depressor phase magnitude was shown to observe due to a rise of stimuli intensiveness down to complete disappearance of pressor reaction.

摘要

在猫的急性实验中表明,由于两种异向且等效的体液刺激作用,出现了双相动脉压变化。初始降压期和随后升压期的幅度确实均小于这些刺激单独作用时的幅度。值得注意的是,总和反应的特征既不取决于血液循环系统中血管活性药物的作用机制,也不取决于这些药物作用潜伏期的差异,而是与刺激强度有关。当刺激强度增加直至升压反应完全消失时,显示出降压期幅度占优势。

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