Faculty of Physical Activity and Sport Sciences, Technical University of Madrid, Madrid, Spain.
Int J Sports Physiol Perform. 2013 Sep;8(5):579-81. doi: 10.1123/ijspp.8.5.579. Epub 2013 Jan 23.
The authors compared ACTN3 R577X genotype and allele frequencies in the majority of all-time-best Spanish judo male athletes (n = 108) and 343 ethnically matched nonathletic men. No between-groups differences were found in allele (P = .077) or genotype distributions (P = .178). Thus, the R577X polymorphism was not significantly associated with the status of being an elite judo athlete, at least in the Spanish population. The contribution of genetics to sports-related phenotype traits is undeniable with some genotypes, of which ACTN3 R577X is currently the leading candidate, partly distinguishing individuals predisposed to either endurance or power sports. However, few athletic events can be categorized as purely power or endurance based. Although genetic testing (ie, for ACTN3 R577X) is already being marketed to predict sports talent and potential of young children, its usefulness is still questionable, at least in competitive judo.
作者比较了在所有西班牙最佳男子柔道运动员（n=108）和 343 名种族匹配的非运动员男性中，ACTN3 R577X 基因型和等位基因频率。在等位基因（P=0.077）或基因型分布（P=0.178）方面，两组之间没有差异。因此，至少在西班牙人群中，R577X 多态性与成为精英柔道运动员的状态没有显著关联。遗传学对与运动相关的表型特征的贡献是不可否认的，某些基因型，其中 ACTN3 R577X 目前是主要候选者，部分区分了倾向于耐力或力量运动的个体。然而，很少有运动项目可以纯粹归类为耐力或力量项目。尽管已经有针对 ACTN3 R577X 的基因检测来预测儿童的运动天赋和潜力，但它的实用性仍存在疑问，至少在竞技柔道中是这样。
