Boffano Paolo, Gallesio Cesare, Campisi Paola, Benech Rodolfo, Roccia Fabio, Berrone Sid
Division of Maxillofacial Surgery, Head and Neck Department, San Giovanni Battista Hospital, University of Turin, Turin, Italy.
J Craniofac Surg. 2013 Jan;24(1):e45-6. doi: 10.1097/SCS.0b013e31826d004c.
Primary bone xanthoma is an extremely rare benign bone tumor histologically characterized by mononuclear macrophage-like cells, abundant foam cells, and multinucleated giant cells. Xanthomas of the bone usually appear as a benign secondary manifestation of some diseases. Therefore, they are denominated primary xanthomas when the other diseases are discarded.We report a peculiar case of primary bone xanthoma of the inferior orbital rim in the absence of hyperlipidemic conditions. Surgical intervention was performed under local anesthesia via a subtarsal 1-cm incision. Histopathological examination confirmed the diagnosis of bone xanthoma. Primary bone xanthomas are extremely rare. Diagnosis of such lesions is challenging and requires both radiographic and histopathological features assessment. A careful work-up and a full lipid profile should be performed to rule out underlying diseases.
原发性骨黄色瘤是一种极其罕见的良性骨肿瘤，组织学上以单核巨噬细胞样细胞、丰富的泡沫细胞和多核巨细胞为特征。骨黄色瘤通常表现为某些疾病的良性继发表现。因此，当排除其他疾病时，它们被称为原发性黄色瘤。我们报告一例在无高脂血症情况下眶下缘原发性骨黄色瘤的特殊病例。在局部麻醉下通过睑板下1厘米切口进行手术干预。组织病理学检查证实为骨黄色瘤。原发性骨黄色瘤极其罕见。诊断此类病变具有挑战性，需要评估影像学和组织病理学特征。应进行仔细的检查和全面的血脂检查以排除潜在疾病。
