Department of Veterinary Large Animal Clinical Sciences, Texas A&M University, College Station, Texas, USA.
J Magn Reson Imaging. 2013 Mar;37(3):632-41. doi: 10.1002/jmri.23862. Epub 2013 Jan 24.
To analyze four clinically applicable diffusion tensor imaging (DTI) protocols (two each in the transverse and sagittal planes) in the normal dog.
Seven healthy Dachshund dogs were scanned with four DTI protocols. Within each plane, identical spatial resolution was used while the number of diffusion-encoding directions and averages varied. Agreement of measured fractional anisotropy (FA) and apparent diffusion coefficient (ADC) was analyzed with Bland-Altman methods, subjective image quality within each plane was compared, and FA and ADC were explored as a function of anatomic location.
There was good agreement in FA and ADC values within each plane. FA had the smallest bias and most precision. No difference was detected in subjective image quality within each plane. FA and ADC were slightly higher cranial to the lumbar intumescence compared to within it.
DTI is a promising tool in the assessment of spinal cord injury (SCI) in the study of dogs with intervertebral disk herniation as a preclinical model of human SCI.
分析四种临床适用的弥散张量成像（DTI）方案（每个平面两种）在正常犬中的应用。
对 7 只健康的达克斯猎犬进行了 4 种 DTI 方案的扫描。在每个平面内，使用相同的空间分辨率，而扩散编码方向和平均值的数量则不同。采用 Bland-Altman 方法分析测量的各向异性分数（FA）和表观扩散系数（ADC）的一致性，比较每个平面内的主观图像质量，并探讨 FA 和 ADC 与解剖位置的关系。
在每个平面内，FA 和 ADC 值的一致性良好。FA 的偏差最小，精度最高。在每个平面内的主观图像质量方面没有差异。与腰椎膨隆内相比，FA 和 ADC 在颅部稍高。
DTI 是评估椎间盘突出症犬的脊髓损伤（SCI）的一种很有前途的工具，可作为人类 SCI 的临床前模型。
