Shevyreva E V, Ivanov A K, Sukhanov D S, Murzina A A
Antibiot Khimioter. 2012;57(7-8):31-7.
To improve the treatment of hepatotoxic responses to antituberculosis polychemotherapy, the impact of remaxol on the biochemical indices and parameters of the antioxidant system in patients with tuberculosis and HIV infection was estimated. The use of remaxol having cytoprotective, anticholestatic, antihypoxitic and antioxidant effects in the treatment of patients with tuberculosis and HIV infection and liver drug damage due to tuberculosis polychemotherapy significantly improved the biochemical indices and lowered the level of the cytolytic and cholestatic syndromes. Remaxol increased the antioxidant system potential and had an antihypoxitic effect.
为改善对抗结核联合化疗肝毒性反应的治疗，评估了雷马克索对结核病合并人类免疫缺陷病毒（HIV）感染患者生化指标及抗氧化系统参数的影响。雷马克索具有细胞保护、抗胆汁淤积、抗缺氧和抗氧化作用，在治疗结核病合并HIV感染及因抗结核联合化疗导致肝药物损伤的患者时，显著改善了生化指标，并降低了细胞溶解和胆汁淤积综合征的水平。雷马克索增强了抗氧化系统的潜能并具有抗缺氧作用。
