Balasaniants G S, Sukhanov D S
Ter Arkh. 2011;83(8):21-4.
The review presents principles of pathogenetic therapy in tuberculosis and current trends in pharmacotherapy: immunocorrection, prophylaxis, chemotherapy side effects management. Immunocorrection is illustrated by treatment with drugs of a polyvalent action - glutoxim and cyclopheron. Mechanisms of their immune action are outlined. As to hepatoprotection, remaxol is an effective hepatoprotecting medicine improving energy supply to hepatocytes and their membranes resistance to lipid peroxidation, reactivating enzymes of antioxidant defense. Remaxol has an antioxidant/antihypoxic action, is the most promosing metabolic corrector with hepatoprotective activity.
免疫纠正、预防、化疗副作用管理。以具有多价作用的药物——谷胱甘肽和环磷酰胺进行治疗为例说明了免疫纠正。概述了它们的免疫作用机制。至于肝脏保护，雷马克索是一种有效的肝脏保护药物，可改善肝细胞的能量供应及其细胞膜对脂质过氧化的抵抗力，激活抗氧化防御酶。雷马克索具有抗氧化/抗缺氧作用，是最有前景的具有肝脏保护活性的代谢调节剂。
