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患有不孕症、盆腔炎和宫外孕的女性体内沙眼衣原体抗体。

Antibodies to Chlamydia trachomatis in women with infertility, pelvic inflammatory disease and ectopic pregnancy.

作者信息

Kihlström E, Lindgren R, Rydén G

机构信息

Department of Clinical Bacteriology, Faculty of Health Sciences, Linköping University, Sweden.

出版信息

Eur J Obstet Gynecol Reprod Biol. 1990 May-Jun;35(2-3):199-204. doi: 10.1016/0028-2243(90)90162-t.

DOI:10.1016/0028-2243(90)90162-t
PMID:2335254
Abstract

Sixty-three women admitted to the gynecological ward at the University Hospital, Linköping, were studied for the presence of antibodies to Chlamydia trachomatis. 48% of infertile women, 78% of women with ectopic pregnancy and 44% of women with pelvic inflammatory disease had higher titer (greater than or equal to 1:128) IgG/IgA/IgM antibodies to C. trachomatis. Among 55 healthy pregnant women, used as controls, 13% had this high antibody titer. Among 30 women with a titer of greater than or equal to 1:128, 33% of previous conceptions resulted in ectopic pregnancy and 31% resulted in child birth. The corresponding figures among women with no antibodies to C. trachomatis were 12% and 60%, respectively. The prevalence of IgA antibodies varied from 22% to 38% in women with pelvic inflammatory disease, ectopic pregnancy or infertility. The results indicate the importance for C. trachomatis in development of sequelae to lower genital tract infections in women.

摘要

对林雪平大学医院妇科病房收治的63名女性进行了沙眼衣原体抗体检测。48%的不孕女性、78%的宫外孕女性和44%的盆腔炎女性沙眼衣原体IgG/IgA/IgM抗体滴度较高(大于或等于1:128)。在作为对照的55名健康孕妇中,13%的人有这种高抗体滴度。在抗体滴度大于或等于1:128的30名女性中,33%的既往妊娠为宫外孕,31%的既往妊娠为分娩。沙眼衣原体抗体阴性的女性中,相应比例分别为12%和60%。盆腔炎、宫外孕或不孕女性中IgA抗体的患病率在22%至38%之间。结果表明沙眼衣原体在女性下生殖道感染后遗症的发生中具有重要作用。

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Infect Dis Obstet Gynecol. 2007;2007:24816. doi: 10.1155/2007/24816. Epub 2007 May 17.
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B-cell-deficient mice develop complete immune protection against genital tract infection with Chlamydia trachomatis.
B细胞缺陷型小鼠对沙眼衣原体生殖道感染产生完全的免疫保护。
Immunology. 1997 Dec;92(4):422-8. doi: 10.1046/j.1365-2567.1997.00378.x.
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Chlamydial serology in genital infections: ImmunoComb versus Ipazyme.生殖道感染中的衣原体血清学检测:免疫组合法与伊帕齐姆法的比较
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