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[海地东南部地区雨季(6月至12月)间恶性疟原虫的流行情况]

[Prevalence of Plasmodium falciparum during the rainy season (June-December) in the southeast district of Haiti].

作者信息

Raccurt C P, Cicéron M, Dossil R, Boncy J

机构信息

Service de parasitologie, laboratoire national de santé publique, Delmas # 33, Port-au-Prince, Haïti.

出版信息

Med Sante Trop. 2012 Oct-Dec;22(4):435-9. doi: 10.1684/mst.2013.0124.

Abstract

This malaria prevalence survey was conducted in Haiti from June through November 2010. The Plasmodium falciparum rate was assessed in 16 municipalities and villages of the southeast district, by examination of thick films from a randomly drawn population sample. The study included 2,126 people aged one to 90 years. P. falciparum was detected among 201 non-febrile subjects. This district, with a P. falciparum rate of 9.5%, is in a low endemic area for malaria. Nonetheless, the infection rates varied considerably from one area to another. Along the coast, the P. falciparum rate ranged from 0 to 34.5%, in four separate categories: four highly infected (mean P. falciparum rate = 21.4% and mean gametocyte rate = 15.3%), four moderately infected (mean P. falciparum rate = 6.1% and gametocyte rate = 5.9%), five slightly infected (mean P. falciparum rate = 3.3% and gametocyte rate = 1.1%) and one uninfected in the interior. No cases of infection were detected in two areas located at an altitude above 600 m. The trophozoite and gametocyte rates varied little as a function of age and thus indicated a low level of protection within the population. This study shows the persistence of endemic malaria at highly variable prevalence levels in this district of Haiti. The development of this region that could be highly desirable to tourists requires the establishment of an appropriate disease control program.

摘要

这项疟疾流行率调查于2010年6月至11月在海地进行。通过检查从随机抽取的人群样本中制备的厚血膜,对东南部地区的16个市镇和村庄的恶性疟原虫感染率进行了评估。该研究纳入了2126名年龄在1至90岁之间的人群。在201名无发热症状的受试者中检测到了恶性疟原虫。该地区的恶性疟原虫感染率为9.5%,属于疟疾低流行区。尽管如此,不同地区的感染率差异很大。沿海地区的恶性疟原虫感染率在0至34.5%之间,分为四类:四个高感染地区(恶性疟原虫平均感染率=21.4%,配子体平均感染率=15.3%),四个中度感染地区(恶性疟原虫平均感染率=6.1%,配子体感染率=5.9%),五个轻度感染地区(恶性疟原虫平均感染率=3.3%,配子体感染率=1.1%),以及一个内陆未感染地区。在海拔600米以上的两个地区未检测到感染病例。滋养体和配子体感染率随年龄变化不大,因此表明人群中的保护水平较低。这项研究表明,在海地的这个地区,地方性疟疾在流行率高度可变的情况下持续存在。该地区的开发对游客极具吸引力,因此需要建立适当的疾病控制项目。

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