Moyou-Somo R, Lehman L G, Awahmukalah S, Ayuk Enyong P
IMPM Medical Research Centre, Yaounde, Cameroon, West Africa.
J Trop Med Hyg. 1995 Oct;98(5):319-24.
This study was conducted from January to December 1992 in Kumba, a town situated in the rain forest region of the South-West Province of Cameroon, and consisted of a longitudinal survey including parasitological and clinical studies. Forty households were chosen for the study and randomly divided into two groups, each with approximately 240 inhabitants aged < or = 15 years. One group received deltamethrin impregnated bednets and the other group had no nets (control). For the months of April, June and August (rainy season), deltamethrin impregnated bednets did not reduce malaria prevalence significantly, but the overall malaria prevalence for all months of the study was significantly reduced (chi 2 MH = 9.17, P = 0.002). Enlarged spleen rates (chi 2 MH = 6.73, P = 0.009) and spleen sizes (P = 0.0002) were also significantly reduced by the nets. However, the reduction in the geometric mean parasite density (GMPD) was not significant. Even though some of these reductions were statistically significant, they were relatively low in a global context compared with previous work done mainly in rural areas. In an urban environment, parents and children usually stay up late, and probably receive many mosquito bites before going to sleep.
本研究于1992年1月至12月在喀麦隆西南省雨林地区的昆巴镇进行,包括一项纵向调查,涵盖寄生虫学和临床研究。该研究选取了40户家庭,随机分为两组,每组约有240名15岁及以下的居民。一组使用了经溴氰菊酯处理的蚊帐,另一组未使用蚊帐(对照组)。在4月、6月和8月(雨季),经溴氰菊酯处理的蚊帐并未显著降低疟疾患病率,但在研究的所有月份中,总体疟疾患病率显著降低(χ²MH = 9.17,P = 0.002)。蚊帐还使脾肿大率(χ²MH = 6.73,P = 0.009)和脾脏大小(P = 0.0002)显著降低。然而,几何平均寄生虫密度(GMPD)的降低并不显著。尽管其中一些降低在统计学上具有显著性,但与之前主要在农村地区开展的工作相比,在整体背景下这些降低幅度相对较小。在城市环境中,父母和孩子通常晚睡,可能在入睡之前会被许多蚊子叮咬。