Gompertz Macarena, Montenegro Cristián, Bufadel María Ester, Defilippi Carlos, Castillo Jaime, Morales Claudia
Sección de Gastroenterología, Departamento de Medicina Interna, Hospital Clínico Universidad de Chile, Santiago, Chile.
Rev Med Chil. 2012 Sep;140(9):1174-8. doi: 10.4067/S0034-98872012000900011.
Ménétrier disease is a rare disorder of the stomach, characterized by giant hypertrophic folds that usually involve the gastric body and fundus, associated to hypoalbuminemia due to serum protein loss across the gastric mucosa. We report a 55-years-old male presenting with abdominal pain, vomiting, weight loss and hypoalbuminemia. Diffuse hypertrophic gastric folds, elevated ulcerated sessile lesions and focal duodenal involvement were seen at endoscopy. Biopsies showed foveolar hyperplasia and glandular atrophy with cystic dilatation. A total gastrectomy was performed with a good outcome.
梅内特里尔病是一种罕见的胃部疾病,其特征是通常累及胃体和胃底的巨大肥厚皱襞,由于血清蛋白通过胃黏膜丢失而伴有低白蛋白血症。我们报告一名55岁男性,表现为腹痛、呕吐、体重减轻和低白蛋白血症。内镜检查可见弥漫性肥厚性胃皱襞、隆起的溃疡性无蒂病变和十二指肠局灶性受累。活检显示小凹增生和腺体萎缩伴囊性扩张。行全胃切除术后效果良好。