Department of Orthopaedic Surgery, Medical Research Institute, Pusan National University School of Medicine, 1-10 Ami-Dong, Seo-Gu, Busan, 602-739, Republic of Korea.
Eur Spine J. 2013 May;22(5):1053-8. doi: 10.1007/s00586-013-2672-1. Epub 2013 Jan 25.
Little data is available on the relationships between sagittal balance and spinopelvic parameters in osteoporosis. We analyzed sagittal spinopelvic parameters in osteoporotic patients.
In this prospective study, the patient and control groups comprised 124 osteoporotic patients and 40 controls. Average age was 72.4 ± 6.8 in the osteoporosis group and 42.7 ± 12.5 in the control group, which was significantly different (P < 0.001). Osteoporotic patients were allocated to two groups by sagittal vertical axis, namely, a sagittal balance group (n = 56) and a sagittal imbalance group (n = 68). All 164 study subjects underwent whole spine lateral radiography, which included hip joints. The radiographic parameters investigated were sacral slope, pelvic tilt, pelvic incidence, thoracic kyphosis, lumbar lordosis, and sagittal vertical axis. Statistical analysis was performed to identify significant differences between the two groups.
Osteoporotic patients and controls were found to be significantly different in terms of sagittal vertical axis, sacral slope, pelvic tilt, lumbar lordosis, and thoracic kyphosis. However, no significant difference was observed between patients and controls in terms of pelvic incidence (P > 0.05). Significant differences were found between the balance and imbalance groups in terms of age, lumbar spine bone mineral density (LSBMD), femoral neck BMD (FNBMD), visual analogue scale (VAS) score, sacral slope, and pelvic incidence. Correlation analysis revealed significant relationships between sagittal parameters and osteoporosis. Stepwise logistic regression analysis revealed that FNBMD and pelvic incidence contributed significantly to sagittal balance.
Sagittal spinopelvic parameters were found to be significantly different in patients and normal controls. Significant relationships were found between sagittal spinopelvic parameters in osteoporotic patients. In particular, low FNBMD and high pelvic incidence were significant parameters in determination of sagittal balance in osteoporotic patients.
关于骨质疏松症患者矢状位平衡与脊柱骨盆参数之间的关系,相关数据较少。我们分析了骨质疏松症患者的矢状位脊柱骨盆参数。
在这项前瞻性研究中,患者组和对照组分别包括 124 名骨质疏松症患者和 40 名对照者。骨质疏松症组的平均年龄为 72.4±6.8 岁,对照组为 42.7±12.5 岁,两组差异有统计学意义(P<0.001)。根据矢状垂直轴将骨质疏松症患者分为两组,即矢状平衡组(n=56)和矢状失平衡组(n=68)。所有 164 例研究对象均接受全脊柱侧位 X 线片检查,包括髋关节。研究的影像学参数包括骶骨倾斜角、骨盆倾斜角、骨盆入射角、胸腰椎后凸角、腰椎前凸角和矢状垂直轴。对两组间的差异进行统计学分析。
骨质疏松症患者与对照组在矢状垂直轴、骶骨倾斜角、骨盆倾斜角、腰椎前凸角和胸腰椎后凸角方面差异有统计学意义。然而,两组间骨盆入射角差异无统计学意义(P>0.05)。平衡组与失平衡组在年龄、腰椎骨密度(LSBMD)、股骨颈骨密度(FNBMD)、视觉模拟评分(VAS)、骶骨倾斜角和骨盆入射角方面差异有统计学意义。相关性分析显示,矢状位参数与骨质疏松症之间存在显著相关性。逐步逻辑回归分析显示,FNBMD 和骨盆入射角对矢状位平衡有显著影响。
骨质疏松症患者与正常对照组的矢状位脊柱骨盆参数存在显著差异。骨质疏松症患者的矢状位脊柱骨盆参数之间存在显著相关性。特别是,FNBMD 低和骨盆入射角高是骨质疏松症患者矢状位平衡的重要决定因素。