Macutkiewicz Christian, Plastow Ricci, Chrispijn Melissa, Filobbos Rafik, Ammori Basil A, Sherlock David J, Drenth Joost Ph, O'Reilly Derek A
Christian Macutkiewicz, Ricci Plastow, Basil A Ammori, David J Sherlock, Derek A O'Reilly, Department of Hepato-Pancreato-Biliary Surgery, North Manchester General Hospital, Manchester M8 5RB, United Kingdom.
World J Hepatol. 2012 Dec 27;4(12):406-11. doi: 10.4254/wjh.v4.i12.406.
Liver cysts are common, affecting 5%-10% of the population. Most are asymptomatic, however 5% of patients develop symptoms, sometimes due to complications and will require intervention. There is no consensus on their management because complications are so uncommon. The aim of this study was to perform a collected review of how a series of complications were managed at our institutions. Six different patients presenting with rare complications of liver cysts were obtained from Hepatobiliary Units in the United Kingdom and The Netherlands. History and radiological imaging were obtained from case notes and computerised radiology. As a result, 1 patient admitted with inferior vena cava obstruction was managed by cyst aspiration and lanreotide; 1 patient with common bile duct obstruction was first managed by endoscopic retrograde cholangiopancreatography and stenting, followed by open fenestration; 1 patient with ruptured cysts and significant medical co-morbidities was managed by percutaneous drainage; 1 patient with portal vein occlusion and varices was managed by open liver resection; 1 patient with infected cysts was treated with intravenous antibiotics and is awaiting liver transplantation. The final patient with a simple liver cyst mimicking a hydatid was managed by open liver resection. In conclusion, complications of cystic liver disease are rare, and we have demonstrated in this series that both operative and non-operative strategies have defined roles in management. The mainstays of treatment are either aspiration/sclerotherapy or, alternatively laparoscopic fenestration. Medical management with somatostatin analogues is a potentially new and exciting treatment option but requires further study.
肝囊肿很常见,影响5% - 10%的人口。大多数肝囊肿无症状,但5%的患者会出现症状,有时是由于并发症,需要进行干预。由于并发症非常罕见,对于其治疗尚无共识。本研究的目的是对我们机构处理一系列并发症的方式进行综述。从英国和荷兰的肝胆科获取了6例出现肝囊肿罕见并发症的不同患者。从病历和计算机放射学资料中获取病史和放射影像学资料。结果,1例因下腔静脉阻塞入院的患者接受了囊肿穿刺抽吸和兰瑞肽治疗;1例胆总管阻塞患者首先接受了内镜逆行胰胆管造影及支架置入术,随后进行了开放性开窗术;1例囊肿破裂且有严重内科合并症的患者接受了经皮引流;1例门静脉闭塞伴静脉曲张的患者接受了开放性肝切除术;1例感染性囊肿患者接受了静脉抗生素治疗,正在等待肝移植。最后1例表现为类似包虫病的单纯肝囊肿患者接受了开放性肝切除术。总之,肝囊肿疾病的并发症很罕见,我们在本系列研究中表明,手术和非手术策略在治疗中都有明确的作用。主要治疗方法是穿刺抽吸/硬化治疗,或者是腹腔镜开窗术。使用生长抑素类似物进行药物治疗是一种潜在的新的、令人兴奋的治疗选择,但需要进一步研究。