Brix O, Bårdgard A, Mathisen S, Tyler N, Nuutinen M, Condo S G, Giardina B
Zoological Laboratory, University of Bergen, Norway.
J Comp Physiol B. 1990;159(6):655-60. doi: 10.1007/BF00691710.
The oxygen binding of whole blood from humans and two arctic mammals, reindeer and muskox, has been studied as a function of carbon dioxide and temperature. All bloods display a marked Bohr effect with Bohr coefficients in the range -0.44- -0.73. The Bohr effect is more pronounced at 20 degrees C. The temperature sensitivity of reindeer and muskox blood expressed by the apparent heat of oxygenation, delta H, is almost three times lower than that of human HbA under the same experimental conditions. This thermodynamic difference gives special benefits to arctic mammals with large heterothermy by safeguarding oxygen unloading at very low ambient temperatures.
对人类以及两种北极哺乳动物（驯鹿和麝牛）全血的氧结合情况进行了研究，该研究将其作为二氧化碳和温度的函数。所有血液均表现出显著的玻尔效应，玻尔系数在-0.44至-0.73范围内。玻尔效应在20摄氏度时更为明显。在相同实验条件下，用氧合表观热（ΔH）表示的驯鹿和麝牛血液的温度敏感性几乎比人类血红蛋白A（HbA）低三倍。这种热力学差异通过在极低环境温度下保障氧卸载，为具有较大异温性的北极哺乳动物带来了特殊益处。
