Lin Andrew H, Phan Hoang-Anh L, Barthel Robert V, Maisel Alan S, Crum-Cianflone Nancy F, Maves Ryan C, Nayak Keshav R
Department of Cardiology, Naval Medical Center San Diego, 34800 Bob Wilson Drive, San Diego, CA 92134, USA.
Mil Med. 2013 Jan;178(1):18-20. doi: 10.7205/milmed-d-12-00226.
In this study, we investigated the incidence and etiology of pericarditis and myopericarditis of military members deployed to Iraq and Kuwait from 2004 through 2008. The importance of acute pericarditis and myopericarditis in the deployed military service member has resurfaced with the reintroduction of the smallpox vaccination by the U.S. Department of Defense in 2002. There are limited epidemiologic data on acute pericarditis and myopericarditis in the general population. As a primary evacuation node for cardiology patients between 2004 and 2008, the United States Military Hospital Kuwait cardiology clinic was uniquely situated to reliably extrapolate epidemiologic data for U.S. Armed Service Members serving in the Middle East. Between these years, approximately 721,600 service members served in Kuwait and Iraq. A total of 70 cases of pericarditis and 9 cases of myopericarditis were diagnosed. This yields an estimated incidence of 7.4 and 0.95 cases per 100,000 per year for pericarditis and myopericarditis, respectively. A total of eleven patients had received the smallpox vaccine 4 to 30 days before being diagnosed with pericarditis or myopericarditis. Four of the eleven patients (36.3%) had pericarditis, with a mean duration of 28.3 days since vaccination. Seven of these eleven (63.6%) patients had myopericarditis, with a mean duration of 13.7 days since smallpox vaccination. The incidence of pericarditis and myopericarditis was lower than previously reported incidence rates in the population. In all cases of myopericarditis and pericarditis, smallpox vaccination was preferentially related to myopericarditis versus pericarditis.
在本研究中，我们调查了2004年至2008年部署到伊拉克和科威特的军人中，心包炎和心肌心包炎的发病率及病因。随着美国国防部于2002年重新引入天花疫苗接种，急性心包炎和心肌心包炎在部署的军人中的重要性再次凸显。关于普通人群中急性心包炎和心肌心包炎的流行病学数据有限。作为2004年至2008年心脏病患者的主要后送节点，科威特美军医院心脏病诊所所处位置独特，能够可靠地推断在中东服役的美国武装部队成员的流行病学数据。在这些年里，约有721,600名军人在科威特和伊拉克服役。共诊断出70例心包炎和9例心肌心包炎。这分别得出心包炎和心肌心包炎的估计发病率为每年每10万人7.4例和0.95例。共有11名患者在被诊断出心包炎或心肌心包炎前4至30天接种了天花疫苗。这11名患者中有4名（36.3%）患心包炎，自接种疫苗以来平均病程为28.3天。这11名患者中有7名（63.6%）患心肌心包炎，自接种天花疫苗以来平均病程为13.7天。心包炎和心肌心包炎的发病率低于此前报道的人群发病率。在所有心肌心包炎和心包炎病例中，天花疫苗接种与心肌心包炎的关联比与心包炎的关联更为密切。
