Abdullaeva L M, Babadzhanova G S, Nazarova D B, Muratova N D, Ashurova U A
Lik Sprava. 2012 Apr-Jun(3-4):104-9.
The article presents hormonal analysis of hypothalamus-hypophysis-ovaries system of 14 patients with sterility as well as of other 15 patients without sterility suffering from benign tumors or tumorous formations. The control group included 6 healthy women. The concentration of hormones in blood serum (FSH-follicle stimulating hormone, LH-lutein hormone, Prolactinum, Testosteronum, Oestradiolum, Progesterone) has been tested in dynamics of a menstrual cycle. Correlation of results of hormonal and histological analysis of a capsule of formation and a biopsy of a tissue of an ovary of these patients has revealed that formation occurrence irrespective of its histological type leads to suppression of the follicular apparatus. These disturbances are more symptomatic for patients with both epithelial cystomas and sterility. It gives evidence that these disturbances can cause sterility. Hormonal disturbances of patients with benign tumors or tumorous formations depend on formation presence, rather than of its histological type. Spontaneous recovery of reproductive function is marked at 35 % of patients. Efficiency of surgery treatment and rehabilitation therapy within the first year after surgery made up 60 %.
本文对14例不育患者以及另外15例患有良性肿瘤或肿瘤样病变的非不育患者的下丘脑-垂体-卵巢系统进行了激素分析。对照组包括6名健康女性。在月经周期动态过程中检测了血清中激素（促卵泡激素、黄体生成素、催乳素、睾酮、雌二醇、孕酮）的浓度。这些患者肿瘤包膜的激素分析结果与卵巢组织活检的相关性表明，无论肿瘤的组织学类型如何，肿瘤的出现都会导致卵泡装置受到抑制。这些紊乱在患有上皮性囊腺瘤且不育的患者中更为明显。这表明这些紊乱可能导致不育。患有良性肿瘤或肿瘤样病变患者的激素紊乱取决于肿瘤的存在，而非其组织学类型。35%的患者生殖功能出现自发恢复。术后第一年手术治疗和康复治疗的有效率为60%。
