2只犬因乙二醇中毒导致血浆乳酸浓度假性升高。
Falsely increased plasma lactate concentration due to ethylene glycol poisoning in 2 dogs.
作者信息
Hopper Kate, Epstein Steven E
机构信息
Department of Veterinary Surgical and Radiological Sciences, University of California, Davis, CA 95616, USA.
出版信息
J Vet Emerg Crit Care (San Antonio). 2013 Jan-Feb;23(1):63-7. doi: 10.1111/j.1476-4431.2012.00825.x.
OBJECTIVE
To describe false increases in plasma lactate concentration measured on point-of-care analyzers in 2 dogs with ethylene glycol (EG) intoxication.
CASE SUMMARY
Two dogs presenting with EG intoxication had extreme increases of plasma lactate concentrations recorded on a point-of-care machine. Laboratory analysis by spectrophotometry of lactate concentration determined these lactate measurements to be erroneous. False increases in plasma lactate concentration were demonstrated in 2 out of 3 point-of-care machines tested.
NEW OR UNIQUE INFORMATION PROVIDED
Glycolate, a toxic metabolite of EG, can interfere with the measurement of plasma lactate by some analyzers and this may delay the correct diagnosis of EG toxicity if not recognized.
目的
描述2只乙二醇（EG）中毒犬在即时检验分析仪上测得的血浆乳酸浓度假性升高情况。
病例摘要
两只出现EG中毒的犬在即时检验仪器上记录到血浆乳酸浓度极度升高。通过分光光度法对乳酸浓度进行实验室分析后确定这些乳酸测量结果有误。在测试的3台即时检验仪器中，有2台出现血浆乳酸浓度假性升高。
提供的新的或独特信息
乙醇酸是EG的一种有毒代谢产物，可干扰某些分析仪对血浆乳酸的测量，如果未被识别，这可能会延迟对EG毒性的正确诊断。
Zotero 插件