Sheta Hussam Mahmoud, Al-Najami Issam, Christensen Heidi Dahl, Madsen Jonna Skov
Department of Anaesthesia and Intensive Care, Lillebaelt Hospital, Kolding, Denmark.
Department of Surgery, Odense University Hospital, Svendborg, Denmark.
Am J Case Rep. 2018 Jun 14;19:689-693. doi: 10.12659/AJCR.908569.
BACKGROUND Ethylene glycol poisoning remains an important presentation to Emergency Departments. Quick diagnosis and treatment are essential to prevent renal failure and life-threating complications. CASE REPORT In this case report, we present a patient who was admitted unconscious to the hospital. Ethylene glycol poisoning was immediately suspected, because the patient had previously been hospitalized with similar symptoms after intake of antifreeze coolant. A urine sample was sent for microscopy and showed multiple calcium oxalate monohydrate (COM) crystals, which supported the clinical suspicion of ethylene glycol poisoning. The patient was treated with continuous intravenous ethyl alcohol infusion and hemodialysis. Two days after admission, the patient was awake and in clinical recovery. CONCLUSIONS Demonstration of COM crystals using microscopy of a urine sample adds valuable information supporting the clinical suspicion of ethylene glycol poisoning, and may serve as an easy, quick, and cheap method that can be performed in any emergency setting.
背景 乙二醇中毒仍是急诊科的一个重要病症。快速诊断和治疗对于预防肾衰竭及危及生命的并发症至关重要。病例报告 在本病例报告中，我们呈现了一名昏迷入院的患者。由于该患者此前摄入防冻液后曾因类似症状住院，故立即怀疑为乙二醇中毒。送检尿液样本进行显微镜检查，结果显示有多个一水合草酸钙（COM）结晶，这支持了乙二醇中毒的临床怀疑。该患者接受了持续静脉输注乙醇及血液透析治疗。入院两天后，患者清醒且临床症状好转。结论 通过尿液样本显微镜检查发现COM结晶为支持乙二醇中毒的临床怀疑增添了有价值的信息，且可作为一种简便、快速且廉价的方法，能在任何急诊情况下进行。
