体外光动力诱导致癌病毒
Photodynamic induction of an oncogenic virus in vitro.
作者信息
Bockstahler L E, Cantwell J M
出版信息
Biophys J. 1979 Jan;25(1):209-13. doi: 10.1016/S0006-3495(79)85286-8.
Abstract
Infectious simian virus 40 (SV40) was induced from SV40-transformed hamster kidney cells by treatment with proflavine and visible fluorescent light. The optimum levels of SV40 induced were about three orders of magnitude above spontaneous background levels observed with untreated cells. No virus induction above background levels was found by treatment of cells with either proflavine or light alone.
摘要
通过用原黄素和可见光处理SV40转化的仓鼠肾细胞，诱导出了传染性猿猴病毒40（SV40）。诱导出的SV40的最佳水平比未处理细胞中观察到的自发背景水平高约三个数量级。单独用原黄素或光处理细胞未发现高于背景水平的病毒诱导情况。
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