Department of Family Medicine, Hallym Sacred Heart Hospital, College of Medicine, Hallym University, Anyang, Korea.
Metabolism. 2013 May;62(5):703-8. doi: 10.1016/j.metabol.2012.11.009. Epub 2013 Jan 26.
There has been no convincing evidence for a direct relation between sodium intake and being overweight. Therefore, we investigated the independent relationship between overweight and sodium intake in human subjects.
Of those aged 19 to 64 years who participated in the 4th Korea National Health and Nutrition Examination Survey, a total of 5955 participants (54% female) were included. Subjects were excluded if they reported unrealistic daily total energy intakes or intentional dietary changes, were pregnant, or were diagnosed with hypertension, diabetes, renal failure, liver cirrhosis, or thyroid disease. Overweight was defined as having a body mass index of 25 kg/m(2) or higher. Sodium intake was calculated from 24-h recall and categorized into quintiles. Multivariate logistic regression was used to test the relationship between sodium intake and being overweight.
Compared to men in the lowest quintile, men in the 4th and 5th quintiles had an increased risk of being overweight with odds ratios (ORs) of 1.37 (95% confidence interval [CI], 1.02-1.82) and 1.67 (95% CI, 1.23-2.27) respectively, after adjusting for confounding factors including soft drink and energy intake. The P value for trend of ORs in each quintile for men was 0.0033. In women, compared to the lowest quintile, the highest quintile had an OR of 1.31(95% CI, 0.96-1.79) and showed a marginally significant trend towards increasing risk of being overweight (P value=.058).
Our findings suggest an independent relationship between high sodium intake and an increased risk of being overweight in adults.
目前尚无令人信服的证据表明钠摄入量与超重之间存在直接关系。因此，我们研究了超重与人类受试者钠摄入量之间的独立关系。
在参与第四次韩国国家健康和营养检查调查的 19 至 64 岁人群中，共纳入 5955 名参与者（54%为女性）。如果报告的每日总能量摄入不现实或有意改变饮食、怀孕、或被诊断患有高血压、糖尿病、肾衰竭、肝硬化或甲状腺疾病，则排除在外。超重定义为身体质量指数为 25kg/m(2)或更高。钠摄入量是根据 24 小时回忆计算的，并分为五分位数。使用多变量逻辑回归检验钠摄入量与超重之间的关系。
与最低五分位数的男性相比，第四和五分位数的男性超重的风险增加，比值比（OR）分别为 1.37（95%置信区间 [CI]，1.02-1.82）和 1.67（95% CI，1.23-2.27），调整了软饮料和能量摄入等混杂因素后。男性每个五分位数的 OR 趋势的 P 值为 0.0033。在女性中，与最低五分位数相比，最高五分位数的 OR 为 1.31（95% CI，0.96-1.79），且超重风险呈上升趋势（P 值=0.058）。
我们的研究结果表明，成人中高钠摄入量与超重风险增加之间存在独立关系。
