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[通过将患者血液灌注经过冷冻保存的肝细胞悬液来治疗严重肝功能不全]

[Treatment of severe hepatic insufficiency by perfusion of patients' blood through a suspension of cryopreserved hepatocytes].

作者信息

Shumakov V I, Arzumanov V S, Onishchenko N A, Sechkin A V, Danilov M A, Shestakova N K, Toshchakov V Iu

出版信息

Khirurgiia (Mosk). 1990 Feb(2):113-6.

PMID:2335879
Abstract

The results of hemoperfusion through a suspension of cryoconserved hepatocytes in 21 patients with severe hepatic insufficiency are analysed. It is shown that the manipulation had a beneficial effect on the clinical and biochemical indices, which was manifested by diminished jaundice and skin pruritus, increased physical activity, improved appetite; reduced levels of bilirubin, transaminase, alkaline phosphatase, bile acids, and cholesterol. The information gained is evidence that the method can be included in the complex treatment of patients with severe hepatic insufficiency.

摘要

分析了21例严重肝功能不全患者通过冷冻保存肝细胞悬液进行血液灌流的结果。结果表明,该操作对临床和生化指标有有益影响,表现为黄疸减轻、皮肤瘙痒减轻、体力活动增加、食欲改善;胆红素、转氨酶、碱性磷酸酶、胆汁酸和胆固醇水平降低。所获得的信息证明该方法可纳入严重肝功能不全患者的综合治疗中。

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