University of Rochester Medical Center, Rochester, NY 14642-8777, USA.
J Clin Oncol. 2013 Apr 1;31(10):1329-35. doi: 10.1200/JCO.2011.39.1870. Epub 2013 Jan 28.
Diagnosis of cancer in a child can be extremely stressful for parents. Bright IDEAS, a problem-solving skills training (PSST) intervention, has been shown to decrease negative affectivity (anxiety, depression, post-traumatic stress symptoms) in mothers of newly diagnosed patients. This study was designed to determine the specificity of PSST by examining its direct and indirect (eg, social support) effects compared with a nondirective support (NDS) intervention.
This randomized clinical trial included 309 English- or Spanish-speaking mothers of children diagnosed 2 to 16 weeks before recruitment. Participants completed assessments prerandomization (T1), immediately postintervention (T2), and at 3-month follow-up (T3). Both PSST and NDS consisted of eight weekly 1-hour individual sessions. Outcomes included measures of problem-solving skill and negative affectivity.
There were no significant between-group differences at baseline (T1). Except for level of problem-solving skill, which was directly taught in the PSST arm, outcome measures improved equally in both groups immediately postintervention (T2). However, at the 3-month follow-up (T3), mothers in the PSST group continued to show significant improvements in mood, anxiety, and post-traumatic stress; mothers in the NDS group showed no further significant gains.
PSST is an effective and specific intervention whose beneficial effects continue to grow after the intervention ends. In contrast, NDS is an effective intervention while it is being administered, but its benefits plateau when active support is removed. Therefore, teaching coping skills at diagnosis has the potential to facilitate family resilience over the entire course of treatment.
儿童癌症的诊断可能会给父母带来极大的压力。已证明,一种解决问题技能培训(PSST)干预措施可以减少新诊断患者母亲的负性情感(焦虑、抑郁、创伤后应激症状)。本研究旨在通过比较 PSST 与非直接支持(NDS)干预的直接和间接(例如社会支持)效应,确定 PSST 的特异性。
这项随机临床试验纳入了 309 名母语为英语或西班牙语的儿童在招募前 2 至 16 周被诊断的母亲。参与者在随机分组前(T1)、干预后即刻(T2)和 3 个月随访时(T3)完成评估。PSST 和 NDS 均由每周 1 小时的 8 次个体会议组成。结果包括解决问题技能和负性情感的测量。
在基线(T1)时,两组之间没有显著差异。除了在 PSST 组中直接教授的解决问题技能水平外,两组在干预后即刻(T2)的结果测量都同样得到改善。然而,在 3 个月随访时(T3),PSST 组的母亲在情绪、焦虑和创伤后应激方面继续显示出显著的改善;而 NDS 组的母亲没有进一步显著的改善。
PSST 是一种有效的、特异性的干预措施,其有益效果在干预结束后仍在不断增加。相比之下,NDS 是一种有效的干预措施,但其益处会在主动支持结束时达到顶峰。因此,在诊断时教授应对技能有可能在整个治疗过程中促进家庭的恢复力。