[Dose fractionation in photon and neutron therapy in the combined treatment of osteogenic sarcoma].

The paper is concerned with the clinical testing of irradiation fractionation in photon therapy, of which the optimum variant was worked out using a method of mathematical simulation. It was conducted in 30 patients with osteogenic sarcoma. In 5 cases a course of photon therapy was supplemented by neutron irradiation. Good tolerance of the proposed scheme by the patients, the absence of contraindications for its administration and marked antitumor efficacy were revealed. Radiation pathomorphism of osteogenic sarcoma after photon and neutron therapy was described.