Chalasani Sreelatha, Bettadahalli Shankar S, Bhupathi Satya V, Aswani Vijay H
Corresponding Author: Vijay H. Aswani, Marshfield Clinic, Department of Internal Medicine & Pediatrics, 1000 North Oak Avenue, Mail stop: 1F3, Marshfield, WI 54449 USA.
Clin Med Res. 2013 Sep;11(3):113-6. doi: 10.3121/cmr.2013.1124. Epub 2013 May 8.
Cystic fibrosis is a recessive autosomal disease caused by mutations in the cystic fibrosis transmembrane conductance regulator gene. Cystic fibrosis-related diabetes (CFRD) is a common comorbidity of cystic fibrosis. Diabetic myonecrosis is a rare self-limited complication of poorly controlled diabetes mellitus that commonly presents with acute, intense pain and swelling of lower extremities and responds well to conservative management. We report the first case of diabetic myonecrosis in a patient with CFRD.
囊性纤维化是一种隐性常染色体疾病,由囊性纤维化跨膜传导调节基因的突变引起。囊性纤维化相关糖尿病(CFRD)是囊性纤维化的常见合并症。糖尿病性肌坏死是控制不佳的糖尿病罕见的自限性并发症,通常表现为下肢急性、剧烈疼痛和肿胀,对保守治疗反应良好。我们报告了首例患有CFRD的患者发生糖尿病性肌坏死的病例。