Shalaby Tamer, Papoutsos Constantinos, Tiemens Louise, Crossingham Iain, Williamson Catherine
ST4 in Acute Medicine, Royal Blackburn Hospital, Blackburn, Lancashire, UK.
Acute Med. 2012;11(4):231-3.
Guillain-Barré syndrome (GBS) is an acute demyelinating disorder of the peripheral nervous system that results in motor weakness, absent reflexes and autonomic nervous system dysfunction. Autonomic failure is reported in approximately 65 % of patients with GBS and usually follows extensive motor involvement. In this case our patient presented with syncope and other signs of autonomic failure before the motor weakness developed. Few cases in the literature have reported features of autonomic failure before established weakness in GBS; to our knowledge, syncope has not been described previously as a presenting feature of GBS.
吉兰-巴雷综合征(GBS)是一种急性周围神经系统脱髓鞘疾病,可导致运动无力、反射消失和自主神经系统功能障碍。据报道,约65%的GBS患者存在自主神经功能衰竭,且通常在广泛的运动受累之后出现。在本病例中,我们的患者在运动无力出现之前就表现出晕厥和其他自主神经功能衰竭的症状。文献中很少有报道GBS患者在出现明确的无力症状之前就有自主神经功能衰竭的特征;据我们所知,晕厥此前尚未被描述为GBS的首发特征。