White Ann, Broder Joshua, Mando-Vandrick Jennifer, Wendell Jonathan, Crowe Jennifer
Department of Advanced Clinical Practice, Duke University Hospital, Duke University School of Nursing, Durham, NC 27710, USA.
Adv Emerg Nurs J. 2013 Jan-Mar;35(1):28-52. doi: 10.1097/TME.0b013e31827145d0.
Patients with aortic disease are some of the highest acuity patients that emergency clinicians encounter. Dissection is the most common aortic catastrophe and involves separation of the aortic layers in a longitudinal fashion leading to diminished perfusion and systemic ischemia. Characteristics of pain, branch vessel involvement, and incidence lead to an understanding of patient presentation, morbidity, and mortality. Diagnosis, selection of diagnostic studies, the degree of preoperative ischemia, and risk of operative mortality can be accomplished using validated clinical decision tools. Emergency interventions are guided by the type of dissection according to the Stanford classification system. Medical management includes pain control and anti-impulse, antihypertensive therapy through vasodilatation and blockage of the sympathetic β-response. The patient may then be evaluated for open surgical intervention, aortic fenestration, endovascularly placed stent grafts, or a combination possibly in a staged approach. Morbidity includes rupture, stroke, paraplegia, acute renal failure, bowel ischemia, and peripheral ischemia.
患有主动脉疾病的患者是急诊临床医生所遇到的病情最危急的患者群体之一。主动脉夹层是最常见的主动脉急症,它涉及主动脉各层呈纵向分离,导致灌注减少和全身缺血。疼痛特征、分支血管受累情况及发病率有助于了解患者的临床表现、发病率和死亡率。使用经过验证的临床决策工具可以完成诊断、诊断性检查的选择、术前缺血程度以及手术死亡率风险评估。根据斯坦福分类系统,急诊干预措施由夹层类型决定。药物治疗包括疼痛控制以及通过血管扩张和阻断交感神经β反应进行的抗搏动、降压治疗。然后可对患者进行评估,以确定是否适合进行开放手术干预、主动脉开窗术、血管内植入支架移植物,或者可能采用分期治疗的联合治疗方法。并发症包括破裂、中风、截瘫、急性肾衰竭、肠缺血和外周缺血。