研究人类血清血液在酒精中毒病理学中的总抗氧化活性。

Tomsk Polytechnic University, 634-050 Tomsk, Russia.

Molecules. 2013 Jan 30;18(2):1811-8. doi: 10.3390/molecules18021811.

The total antioxidant activity (TAA) of human serum blood of patients suffering from alcoholism was tested by cathode voltammetry with a model process of oxygen electroreduction. A known spectrophotometrical method was used for comparison. As results the total antioxidant activity of serum blood of patients with alcoholism was estimated by voltammetry during therapy in hospital. It was shown the TAA of serum blood of patients in pathology before and after treatment is lower than that one of healthy people. However, during the process of 10 days of alcoholism treatment the TAA coefficient increases. The relationship between the coefficient of total antioxidant activity of human serum blood and the stage of treatment was detected.

采用模型氧还原电化学法，通过阴极伏安法对酗酒患者的人血清血总抗氧化活性（TAA）进行测试，同时与已知的分光光度法进行比较。结果表明，在医院治疗期间通过伏安法估计了酗酒患者的血清血总抗氧化活性。结果表明，酗酒患者治疗前后的血清血 TAA 低于健康人的 TAA。然而，在 10 天的酗酒治疗过程中，TAA 系数增加。检测了人血清血总抗氧化活性系数与治疗阶段之间的关系。