Department of Obstetrics and Gynecology, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
J Med Virol. 2013 May;85(5):935-8. doi: 10.1002/jmv.23531. Epub 2013 Jan 30.
A 31-year-old woman contracted acute varicella at 13 weeks of gestation. Severe hydrops fetalis, hepatomegaly, and intrauterine fetal death were detected at 16 weeks of gestation by ultrasound examinations. An examination at autopsy, histopathology, and polymerase chain reaction (PCR) provided evidence of varicella-zoster virus (VZV) infection of the fetus. Second trimester intrauterine fetal death caused by mother to fetus infection of VZV is extremely rare.
一名 31 岁女性于妊娠 13 周时感染急性水痘。16 周时超声检查发现严重胎儿水肿、肝肿大和宫内胎儿死亡。尸检、组织病理学和聚合酶链反应 (PCR) 检查结果均证实胎儿感染水痘-带状疱疹病毒 (VZV)。妊娠中期因母亲传染给胎儿的 VZV 导致宫内胎儿死亡极为罕见。
