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用于周围神经修复的仿生神经连接

A Bionic Neural Link for peripheral nerve repair.

作者信息

Xu Yong Ping, Yen Shih-Cheng, Ng Kian Ann, Liu Xu, Tan Ter Chyan

机构信息

Dept of Electrical and Computer Engineering, National University of Singapore, 4 Engineering Dr 3, Singapore.

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2012;2012:1335-8. doi: 10.1109/EMBC.2012.6346184.

Abstract

Peripheral nerve injuries with large gaps and long nerve regrowth paths are difficult to repair using existing surgical techniques, due to nerve degeneration and muscle atrophy. This paper proposes a Bionic Neural Link (BNL) as an alternative way for peripheral nerve repair. The concept of the BNL is described, along with the hypothetical benefits. A prototype monolithic single channel BNL has been developed, which consists of 16 neural recording channels and one stimulation channel, and is implemented in a 0.35-µm CMOS technology. The BNL has been tested in in-vivo animal experiments. Full function of the BNL chip has been demonstrated.

摘要

由于神经变性和肌肉萎缩,使用现有手术技术修复存在大间隙和长神经再生路径的周围神经损伤很困难。本文提出了一种仿生神经链路(BNL)作为周围神经修复的替代方法。描述了BNL的概念以及假设的益处。已开发出一种原型单片单通道BNL,它由16个神经记录通道和一个刺激通道组成,并采用0.35-μm CMOS技术实现。该BNL已在体内动物实验中进行了测试。已证明BNL芯片的全部功能。

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