College of Microelectronics, Beijing University of Technology, Ping Le Yuan 100# Chao Yang District, Beijing, China.
Advanced Photonics Institute, Beijing University of Technology, Ping Le Yuan 100# Chao Yang District, Beijing, China.
J Healthc Eng. 2021 Aug 27;2021:4153155. doi: 10.1155/2021/4153155. eCollection 2021.
This paper presents chip implementation of the integrated neural recording and stimulation system with stimulation-induced artifact suppression. The implemented chip consists of low-power neural recording circuits, stimulation circuits, and action potential detection circuits. These circuits constitute a closed-loop simultaneous neural recording and stimulation system for biomedical devices, and a proposed artifact suppression technique is used in the system. Moreover, this paper also presents the measurement and experiment results of the implemented 4-to-4 channel neural recording and stimulation chip with 0.18 m CMOS technology. The function and efficacy of simultaneous neural recording and stimulation is validated in both and animal experiments.
本文提出了一种具有刺激诱发伪影抑制功能的集成神经记录和刺激系统的芯片实现。所实现的芯片由低功耗神经记录电路、刺激电路和动作电位检测电路组成。这些电路构成了用于生物医学设备的闭环同时神经记录和刺激系统，并在系统中使用了一种提出的伪影抑制技术。此外，本文还介绍了采用 0.18μm CMOS 技术实现的 4 对 4 通道神经记录和刺激芯片的测量和实验结果。在 和动物实验中验证了同时进行神经记录和刺激的功能和效果。
