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哮喘吸入器记录中吸入动作的自动识别与精确时间检测。

Automatic identification and accurate temporal detection of inhalations in asthma inhaler recordings.

作者信息

Holmes Martin S, Le Menn Marine, D'Arcy Shona, Rapcan Viliam, MacHale Elaine, Costello Richard W, Reilly Richard B

机构信息

Trinity Center for Bioengineering, Trinity College Dublin, Dublin 2, Ireland.

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2012;2012:2595-8. doi: 10.1109/EMBC.2012.6346495.

Abstract

Asthma is chronic airways disease characterized by recurrent attacks of breathlessness and wheezing. Adherence to medication regimes is a common failing for asthmatic patients and there exists a requirement to monitor such patients' adherence. The detection of inhalations from recordings of inhaler use can provide empirical evidence about patients' adherence to their asthma medication regime. Manually listening to recordings of inhaler use is a tedious and time consuming process and thus an algorithm which can automatically and accurately carry out this task would be of great value. This study employs a recording device attached to a commonly used dry powder inhaler to record the acoustic signals of patients taking their prescribed medication. An algorithm was developed to automatically detect and accurately demarcate inhalations from the acoustic signals. This algorithm was tested on a dataset of 255 separate recordings of inhaler use in real world environments. The dataset was obtained from 12 asthma outpatients who attended a respiratory clinic over a three month period. Evaluation of the algorithm on this dataset achieved sensitivity of 95%, specificity of 94% and an accuracy of 89% in detecting inhalations compared to manual inhalation detection.

摘要

哮喘是一种慢性气道疾病,其特征为反复发作的呼吸急促和喘息。坚持用药方案是哮喘患者常见的不足之处,因此需要监测此类患者的用药依从性。从吸入器使用记录中检测吸入情况可为患者对哮喘药物治疗方案的依从性提供实证依据。人工聆听吸入器使用记录是一个繁琐且耗时的过程,因此能够自动且准确执行此任务的算法将具有很大价值。本研究使用连接到常用干粉吸入器的记录设备来记录患者服用规定药物时的声学信号。开发了一种算法,用于从声学信号中自动检测并准确划分出吸入情况。该算法在一个包含255个在现实环境中单独的吸入器使用记录的数据集上进行了测试。该数据集来自12名哮喘门诊患者,他们在三个月的时间里到呼吸科诊所就诊。与人工吸入检测相比,该算法在这个数据集上的评估在检测吸入情况时达到了95%的灵敏度、94%的特异性和89%的准确率。

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