Hu Zhe, Troyk Philip, DeMichele Glenn, Kayvani Kevin, Suh Sungjae
Sigenics Inc., Chicago, IL 60616, USA.
Annu Int Conf IEEE Eng Med Biol Soc. 2012;2012:2788-91. doi: 10.1109/EMBC.2012.6346543.
Activated Iridium Oxide Film (AIROF) microelectrodes are regarded as advantage for stimulation of neural tissue owing to their superior charge injection capabilities, as compared to other noble-metal based electrodes. Including AIROF electrodes within an implantable neural stimulator can be challenging since the stimulator fabrication steps often involve elevated temperatures at which the AIROF can be damaged. In this work, a wireless neural stimulator application-specific-integrated-circuit (ASIC) was used to intrinsically activate iridium microelectrodes. This intrinsic activation allows for the growth of the AIROF as the final assembly step after the entire device is assembled, thus avoiding stress on the AIROF. Since a typical neural stimulator is essentially a current-controlled driver with voltage compliance limits, its output waveform can be tuned to match the traditional voltage pulsing/ramp activation waveform. Here the feasibility of the current driven activation of iridium electrodes, over a wireless link, is demonstrated.
与其他基于贵金属的电极相比,氧化铱薄膜(AIROF)微电极因其卓越的电荷注入能力,被视为刺激神经组织的优势电极。将AIROF电极集成到植入式神经刺激器中具有挑战性,因为刺激器的制造步骤通常涉及高温,而在此温度下AIROF可能会受损。在这项工作中,一种无线神经刺激器专用集成电路(ASIC)被用于对铱微电极进行本征激活。这种本征激活允许在整个设备组装完成后的最后组装步骤中生长AIROF,从而避免对AIROF造成应力。由于典型的神经刺激器本质上是一个具有电压依从性限制的电流控制驱动器,其输出波形可以进行调整,以匹配传统的电压脉冲/斜坡激活波形。本文展示了通过无线链路对铱电极进行电流驱动激活的可行性。