Cogan Stuart F, Troyk Philip R, Ehrlich Julia, Plante Timothy D
EIC Laboratories Inc, 111 Downey St, Norwood, MA 02062, USA.
IEEE Trans Biomed Eng. 2005 Sep;52(9):1612-4. doi: 10.1109/TBME.2005.851503.
The charge-injection limits of activated iridium oxide electrodes (AIROF) and PtIr microelectrodes with similar geometric area and shape have been compared in vitro using a stimulation waveform that delivers cathodal current pulses with current-limited control of the electrode bias potential in the interpulse period. Charge-injection limits were compared over a bias range of 0.1-0.7 V (versus Ag/AgCl) and pulse frequencies of 20, 50, and 100 Hz. The AIROF was capable of injecting between 4 and 10 times the charge of the PtIr electrode, with a maximum value of 3.9 mC/cm2 obtained at a 0.7 V bias and 20 Hz frequency.
在体外实验中，我们采用一种刺激波形，该波形在脉冲间期通过对电极偏置电位进行限流控制来施加阴极电流脉冲，以此比较了具有相似几何面积和形状的活化氧化铱电极（AIROF）和铂铱微电极的电荷注入极限。在0.1 - 0.7 V（相对于Ag/AgCl）的偏置范围以及20、50和100 Hz的脉冲频率下对电荷注入极限进行了比较。AIROF能够注入的电荷量是铂铱电极的4至10倍，在0.7 V偏置和20 Hz频率下获得的最大值为3.9 mC/cm²。
