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蔬菜和水果提取物对体外苯并(a)芘的抗诱变活性

[Antimutagenic activity of vegetable and fruit extracts against in-vitro benzo(a)pyrene].

作者信息

Edenharder R, John K, Ivo-Boor H

机构信息

Hygiene-Institut, Johannes-Gutenberg-Universität Mainz.

出版信息

Z Gesamte Hyg. 1990 Mar;36(3):144-7.

PMID:2336853
Abstract

About 80% of the juices from twenty vegetables and fruits showed antimutagenic activity when tested in the presence of the mutagen and carcinogen benzo[a]pyrene using the Ames' Salmonella/microsome assay. In a standardized test system juices from raw celeriac, broccoli, red cabbage, carrots, green, peppers, lettuce, asparagus, apricots, red-currants, gooseberries, raspberries, and pineapple showed more than 50% inhibition. Leek, kohlrabi, cucumber, zucchini, French beans, fennel leaves, rhubarb, and sweet cherries were less effective. No antimutagenic activity was detected in onions, Chinese cabbage, radish, and white cabbage. Cooking considerably reduced the antimutagenic activity of celeriac, leek, broccoli, French beans, carrots, asparagus, cherries, and pineapple, but was ineffective or only moderately effective with kohlrabi, zucchini, cucumber, fennel leaves, lettuce, apricots, red-currants, gooseberries, and raspberries.

摘要

当使用艾姆斯氏沙门氏菌/微粒体试验,在诱变剂和致癌物苯并[a]芘存在的情况下进行测试时,二十种蔬菜和水果中约80%的汁液显示出抗诱变活性。在标准化测试系统中,生芹菜、西兰花、红甘蓝、胡萝卜、青椒、生菜、芦笋、杏子、红醋栗、醋栗、覆盆子和菠萝的汁液显示出超过50%的抑制作用。韭菜、球茎甘蓝、黄瓜、西葫芦、法国豆、茴香叶、大黄和甜樱桃的效果较差。在洋葱、大白菜、萝卜和白甘蓝中未检测到抗诱变活性。烹饪会显著降低芹菜、韭菜、西兰花、法国豆、胡萝卜、芦笋、樱桃和菠萝的抗诱变活性,但对球茎甘蓝、西葫芦、黄瓜、茴香叶、生菜、杏子、红醋栗、醋栗和覆盆子无效或效果一般。

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