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一种使用α-羟基酸、维生素C和氧气的新型浅表化学换肤术治疗黄褐斑的疗效与安全性。

Efficacy and safety of a new superficial chemical peel using alpha-hydroxy acid, vitamin C and oxygen for melasma.

作者信息

Kim Won-Serk

机构信息

Department of Dermatology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

出版信息

J Cosmet Laser Ther. 2013 Feb;15(1):21-4. doi: 10.3109/14764172.2012.748199.

Abstract

BACKGROUND

Facial skin pigmentary disorders can be resistant to conventional treatment. Superficial chemical peel is an effective and safe treatment in pigmentary problems including melasma, post-inflammatory hyperpigmentation and aging spots.

OBJECTIVE

To assess the efficacy and safety of new superficial chemical peel (Melasma peel, Theraderm®), this is composed of alpha-hydroxy acid (AHAs), vitamin C and oxygen for melasma.

METHODS

Twenty-five ethnic Korean patients (Fitzpatrick skin phototypes IV and V) with moderate to severe melasma were enrolled. The patients underwent four treatments at 1-2-week intervals for 8 weeks. Clinical improvement was evaluated on a 5-point scale by participants and by the same dermatologist, and adverse effects were checked during the study.

RESULTS

Improvement in the degree of pigmentation, pores, and evenness were noted. Significant clinical improvement of hyperpigmentation was evident. No adverse effects were reported.

CONCLUSION

New superficial chemical peel using AHAs, vitamin C and oxygen is an effective and very safe treatment for melasma.

摘要

背景

面部皮肤色素沉着紊乱对传统治疗可能具有抗性。浅表化学剥脱术是治疗包括黄褐斑、炎症后色素沉着和老年斑在内的色素沉着问题的一种有效且安全的治疗方法。

目的

评估新型浅表化学剥脱术(黄褐斑剥脱术,Theraderm®)的疗效和安全性,该剥脱术由α-羟基酸(AHA)、维生素C和氧气组成,用于治疗黄褐斑。

方法

招募了25名患有中度至重度黄褐斑的韩国患者(Fitzpatrick皮肤光类型IV和V)。患者每隔1 - 2周接受4次治疗,持续8周。由参与者和同一位皮肤科医生采用5分制评估临床改善情况,并在研究期间检查不良反应。

结果

色素沉着程度、毛孔和肤色均匀度均有改善。色素沉着有显著的临床改善。未报告不良反应。

结论

使用AHA、维生素C和氧气的新型浅表化学剥脱术是治疗黄褐斑的一种有效且非常安全的方法。

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