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黑皮剥脱术与25%三氯乙酸剥脱术治疗轻至中度寻常痤疮的疗效及安全性比较评估:一项半脸对照研究

Comparative evaluation of therapeutic efficacy and safety of black peel versus 25% trichloroacetic acid peel in mild to moderate acne vulgaris: a split face study.

作者信息

Puri Neerja, Kumar Sumir, Kaur Sameer, Brar B K

机构信息

Department of Dermatology, GGS Medical College, Faridkot, Punjab, India.

出版信息

J Cutan Aesthet Surg. 2024 Jan-Mar;17(1):11-18. doi: 10.4103/JCAS.JCAS_69_23.

Abstract

INTRODUCTION

Peeling has withstood the test of time as a simple, minimally invasive method to renew the skin, despite the introduction of more advanced procedures like lasers.

MATERIALS AND METHODS

Thirty patients (or 60 sites) with age ranging from 15 to 45 years with mild-to-moderate acne vulgaris were included in the study. Assessment at baseline was done by the global acne grading system score for including mild and moderate acne patients.

RESULTS

On grading the improvement according to the 5-point Global Assessment Scale (GAS), it was found that in area A (black peel), 6.7% of patients showed excellent improvement, 86.7% of patients showed good improvement, and 6.7% of patients showed fair improvement. In area B (25%TCA peel), 6.7% of patients showed excellent improvement, 80% of patients showed good improvement, and 13.3% of patients showed fair improvement.

DISCUSSION

None of the patients showed poor or worse outcomes in any of the areas. The difference between the groups was not significant ( 0.688).

CONCLUSION

There is a paucity of data in the literature regarding the comparison of black peel with other conventional peels in the treatment of acne vulgaris. To the best of our knowledge, this is the first study comparing black peel with TCA peel in the treatment of acne vulgaris.

摘要

引言

尽管出现了激光等更先进的治疗方法,但皮肤剥脱术作为一种简单、微创的皮肤更新方法,经受住了时间的考验。

材料与方法

本研究纳入了30例年龄在15至45岁之间、患有轻至中度寻常痤疮的患者(共60个部位)。通过全球痤疮分级系统评分对包括轻度和中度痤疮患者在内的基线情况进行评估。

结果

根据5分制全球评估量表(GAS)对改善情况进行分级后发现,在A区(黑肤剥脱术),6.7%的患者显示出极佳改善,86.7%的患者显示出良好改善,6.7%的患者显示出中等改善。在B区(25%三氯乙酸剥脱术),6.7%的患者显示出极佳改善,80%的患者显示出良好改善,13.3%的患者显示出中等改善。

讨论

在任何一个区域,均无患者出现较差或更差的治疗结果。两组之间的差异不显著(P = 0.688)。

结论

关于黑肤剥脱术与其他传统剥脱术在治疗寻常痤疮方面的比较,文献中的数据较少。据我们所知,这是第一项比较黑肤剥脱术与三氯乙酸剥脱术治疗寻常痤疮的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40f4/11086936/b3fefcdb1bba/JCAS-17-11-g001.jpg

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