Ikegame Yuka
Stem Cell Res Ther. 2013 Jan 31;4(1):9. doi: 10.1186/scrt157.
Owing to the several advantages that they have over other cells, mesenchymal stem cells are among the most promising tools in stem cell therapy after ischemic stroke. Mesenchymal stem cells can be obtained from various sources. Therefore, a wide range of careful comparative studies of these cells is required, from the preclinical stage (in vitro and in vivo) to the clinical stage, in order to develop the best therapy with the most appropriate cell type. An in vivo study in this issue of Stem Cell Research & Therapy compares the therapeutic potential of two cell types, obtained from bone marrow and adipose tissue, in a rodent stroke model. This commentary discusses the significance of comparative studies of mesenchymal stem cells, including the related article in translational research.
由于间充质干细胞相对于其他细胞具有多种优势，它们是缺血性中风后干细胞治疗中最有前景的工具之一。间充质干细胞可以从多种来源获取。因此，需要从临床前阶段（体外和体内）到临床阶段，对这些细胞进行广泛而细致的比较研究，以便开发出使用最合适细胞类型的最佳治疗方法。本期《干细胞研究与治疗》中的一项体内研究在啮齿动物中风模型中比较了从骨髓和脂肪组织中获取的两种细胞类型的治疗潜力。本评论讨论了间充质干细胞比较研究的意义，包括转化研究中的相关文章。
