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三氯异氰尿酸(TCCA):一种高效的绿色试剂,可用于激活硫代糖苷进行水解。

Trichloroisocyanuric acid (TCCA): an efficient green reagent for activation of thioglycosides toward hydrolysis.

机构信息

Department of Chemistry, Jadavpur University, Kolkata 700 032, India.

出版信息

Carbohydr Res. 2013 Mar 22;369:10-3. doi: 10.1016/j.carres.2013.01.001. Epub 2013 Jan 9.

DOI:10.1016/j.carres.2013.01.001
PMID:23370167
Abstract

Trichloroisocyanuric acid (TCCA), an inexpensive, commercially available, and non-toxic reagent has been used for the activation of thioglycosides toward their hydrolysis to the corresponding hemiacetals in high to excellent yields. The methodology provides a mild reaction condition for dealing with compounds containing acid sensitive functional groups.

摘要

三氯异氰尿酸(TCCA)是一种廉价、可商购且无毒的试剂,已被用于激活硫代糖苷使其水解为相应的半缩醛,产率高至优秀。该方法为处理含有酸性敏感官能团的化合物提供了温和的反应条件。

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