Department of Histopathology, King Edward Memorial Hospital, Subiaco, Western Australia.
Int J Gynecol Pathol. 2013 Mar;32(2):171-5. doi: 10.1097/PGP.0b013e31825b81fd.
Lymphangiomas of the ovary are rare and are usually unilateral. We present a 50-yr-old patient who presented with irregular bleeding secondary to multiple uterine leiomyomas who was found to have bilateral ovarian lymphangiomas. There was no evidence of pelvic lymphatic obstruction or of lymphadenopathy, and this appeared to exclude the possibility of acquired lymphangiectasia. The ovarian tumors were associated with a prominent smooth muscle cell component that partly surrounded many of the dilated vascular spaces to the extent that the diagnoses of lymphangioleiomyoma and lymphangioleiomyomatosis were also considered. However, there was no clinical evidence of lymphangioleiomyomatosis in other sites and the smooth muscle cells did not express melanocytic markers immunohistochemically. Lymphangioma and lymphangioleiomyoma should be considered in the differential diagnosis of bilateral, multicystic ovarian neoplasms.
卵巢淋巴管瘤很少见，通常为单侧。我们报告了一位 50 岁的患者，因多发性子宫肌瘤引起不规则出血，发现双侧卵巢淋巴管瘤。没有盆腔淋巴阻塞或淋巴结病的证据，这似乎排除了获得性淋巴管扩张的可能性。卵巢肿瘤与突出的平滑肌细胞成分有关，部分围绕许多扩张的血管腔，以至于也考虑了淋巴管平滑肌瘤病和淋巴管平滑肌瘤病的诊断。然而，在其他部位没有淋巴血管平滑肌瘤病的临床证据，平滑肌细胞免疫组织化学也不表达黑色素细胞标志物。在双侧多房性卵巢肿瘤的鉴别诊断中应考虑淋巴管瘤和淋巴管平滑肌瘤。
